Selective recognition of RNA helices containing dangling ends by a quinoline derivative.
نویسندگان
چکیده
منابع مشابه
A uniform mechanism correlating dangling-end stabilization and stacking geometry.
The geometry of the dangling base in 105 published structures (from X-ray/NMR) containing single-stranded overhangs has been analyzed and correlated to the thermodynamic stabilization found (UV) for the corresponding dangling base/closing basepair combination in short oligonucleotides. The study considers most combinations of closing basepairs, sequence and dangling base residue type, attached ...
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The role of stacking in terminal base-pair formation was studied by comparison of the stability increments for dangling ends to those for fully formed base pairs. Thermodynamic parameters were measured spectrophotometrically for helix formation of the hexanucleotides AGGCCUp, UGGCCAp, CGGCCGp, GCCGGCp, and UCCGGAp and for the corresponding pentanucleotides containing a 5'-dangling end on the GG...
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ورودعنوان ژورنال:
- Chembiochem : a European journal of chemical biology
دوره 8 14 شماره
صفحات -
تاریخ انتشار 2007